EDCTP Call for Proposals: ‘Strategic Action for Overcoming Drug Resistance in Malaria’ Program

Deadline: 30 October 2018

The European & Developing Countries Clinical Trials Partnership (EDCTP) is seeking proposals for a program entitled “Strategic action for overcoming drug resistance in malaria”.

The purpose of this Call for Proposals is to support one large-scale strategic action (clinical research activities) that is part of a bigger portfolio of clinical trials with the capacity to develop new and diverse antimalarial drugs against Plasmodium falciparum and/or Plasmodium vivax, including combination therapies that may be used for treatment or chemoprevention of malaria in sub-Saharan Africa.

Grant Information

  • The call budget is EUR 22 million.
  • The requested EDCTP contribution per project should not exceed EUR 22 million.
  • EDCTP considers that proposals for a large-scale strategic action of between 48 and 60 months duration would allow this specific challenge to be addressed appropriately.

Expected Impact

The action funded under this Call for Proposals should contribute to increased international cooperation among researchers and funders, catalyse research synergies, and leverage resources and investments in order to achieve rapid advances in the development of new or improved anti-malarial drugs or drug combinations. Proposals that leverage major relevant financial contributions from funders other than the EDCTP Association will be considered to have a higher impact. The action should have the potential to achieve maximum impact in the field and to make a significant contribution to the objectives of the EDCTP programme, and in particular:

  • contribute towards combatting drug resistance through development of new or improved antimalarial products
  • lead to the advancement of new drugs and/or drug combinations, with the aim of registration of new drug(s) and/or drug combinations for treatment and prevention of malaria in sub-Saharan Africa and globally
  • contribute to the reduction of malaria mortality and morbidity in sub-Saharan Africa, particularly in pregnant women, infants and children and thus contribute to achieving SDG 3 ‘Ensure healthy lives and promote well-being for all at all ages’.

Eligibility Criteria

A proposal/application will only be eligible if:

  • its content corresponds wholly or in part to the topic/contest description for which it is submitted
  • it complies with the eligibility conditions set out below, depending on the type of action:
    • Consortia comprising a minimum of three independent legal entities are eligible to apply. Two of the legal entities shall be established in two different Participating States (European Partner States) and one of the legal entities must be established in a sub-Saharan African country. All three legal entities shall be independent of each other.
    • ‘Sole participants’ formed by several legal entities (e.g. European Research Infrastructure Consortia, European Groupings of Territorial Cooperation, central purchasing bodies) are eligible if the above-mentioned minimum conditions are satisfied by the legal entities forming together the sole participant.

How to Apply

Interested applicants must apply online via given website.

Eligible Countries:

  • Europe: Austria, Denmark, Finland, France, Germany, Ireland, Italy, Luxembourg, Netherlands, Norway, Portugal, Spain, Sweden and United Kingdom.
  • Sub-Saharan Africa: Angola, Benin, Botswana, Burkina Faso, Burundi, Cameroon, Cape Verde, Central African Republic, Chad, Comoros, Congo (Democratic Republic), Congo (Republic), Côte d’Ivoire, Djibouti, Eritrea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Kenya, Lesotho, Liberia, Madagascar, Malawi, Mali, Mauritania, Mauritius, Mozambique, Namibia, Niger, Nigeria, Rwanda, São Tomé and Príncipe, Senegal, Seychelles, Sierra Leone, Somalia, South Africa, South Sudan, Sudan, Swaziland, Tanzania, Togo, Uganda, Zambia, Zimbabwe.

For more information, please visit EDCTP.

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