Medications Development to Treat Substance Use Disorders

Deadline: 25 July 2019

The National Institute on Drug Abuse (NIDA) is currently seeking proposals from eligible entities for its program titled- Strategic Alliances for Medications Development to Treat Substance Use Disorders.

The purpose of this program is to support research that advances compounds towards FDA approval by leveraging NIDA funds with the strengths and resources of outside organizations, such as for-profit and not-for-profit entities, including academic institutions, pharmaceutical and biotechnology companies, private and public foundations, and small businesses.

Priority Areas

This program encourages, but is not limited to, the following medications development stages:

Lead optimization of new chemical entities identified through assay screens as having promise as
SUD treatments.
Preclinical characterization of pharmacological or biological-based therapies, within appropriate
animal models of behavior, and / or IND enabling studies including toxicity and pharmacokinetic
(PK) / pharmacodynamic (PD) studies.
Clinical Development
Phase I clinical trials (e.g., safety and interaction studies, human laboratory studies assessing
subjective effects of a medication on targeted drug of abuse).
Pilot or proof-of-concept studies to assess efficacy.
Phase II clinical trials to assess efficacy.
Phase III clinical trials for NDA requirements.

Funds Available

The estimated total program funding will be $3,000,000.

Eligibility Criteria

Private institutions of higher education
Native American tribal governments (Federally recognized)
Special district governments
County governments
City or township governments
Public housing authorities/Indian housing authorities
Public and State controlled institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
State governments
Independent school districts
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Alaska Native and Native Hawaiian Serving Institutions
Asian American Native American Pacific Islander Serving Institutions (AANAPISISs)
Eligible Agencies of the Federal Government
Faith-based or Community-based Organizations
Hispanic-serving Institutions
Historically Black Colleges and Universities (HBCUs)
Indian/Native American Tribal Governments (Other than Federally Recognized)
Non-domestic (non-U.S.) Entities (Foreign Organizations)
Regional Organizations
Tribally Controlled Colleges and Universities (TCCUs)
U. S. Territory or Possession.