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Infectious Disease Clinical Trial Development Grant Programme

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Deadline: 19-May-2026

The Infectious Disease Clinical Trial Development Grant Programme supports researchers in low- and middle-income countries (LMICs) to develop innovative clinical trial ideas that optimize licensed infectious disease interventions. The programme offers up to £200,000 per award for up to 24 months to support preparatory research that can lead to future late-stage randomized controlled trials (RCTs).

Eligible teams must include at least 2 applicants (lead + coapplicant), with at least 50% of the team based in Africa, South Asia, or South-East Asia, and the administering organisation must also be located in those regions. Projects must focus on priority infectious diseases, include strong stakeholder engagement, data planning, capacity building, and transdisciplinary collaboration, and show how the work will progress toward future clinical trials.

Overview

The Infectious Disease Clinical Trial Development Grant Programme funds early-stage clinical trial development research for infectious diseases in LMIC settings.

Its goal is to help research teams design and prepare high-quality, scalable clinical trial concepts that can improve the use of licensed interventions in real-world settings.

Key Funding Details

What Is This Grant Programme?

This programme supports research that lays the groundwork for future clinical trials, especially late-stage randomized controlled trials (RCTs).

It is not mainly for running a full late-stage trial now. Instead, it funds the development work needed before a major clinical trial can be launched.

Main Purpose

The grant is designed to help teams:

Priority Disease Areas

Projects must focus on infectious diseases within the programme’s priority areas.

Eligible Disease Focus Areas

What Kind of Research Is Supported?

The programme supports clinical trial development research, not just general infectious disease research.

Projects should clearly show how the proposed work will lead to a future clinical trial of a licensed intervention.

Strong proposals should include:

What Costs Can Be Funded?

The grant can cover a broad range of eligible research costs.

Eligible Budget Categories

Who Is Eligible?

This is a team-based funding opportunity.

Team Requirements

Applicants must form a team with:

All applicants must be based in eligible regions and intend to remain there for the full project duration.

Lead Applicant Requirements

The lead applicant must be:

Coapplicant Requirements

Coapplicants:

Collaborators

Collaborators may:

However:

Eligible Organisations

The administering organisation must be located in:

Eligible organisation types include:

The organisation must be able to:

What Must the Research Proposal Include?

A competitive proposal should be detailed, practical, and clearly linked to future clinical trials.

Required Proposal Elements

Why This Grant Matters

This programme is important because many promising interventions fail to reach effective real-world use without strong trial development work.

It helps research teams:

How to Apply / What to Do

Step-by-Step Application Strategy

  1. Choose an eligible infectious disease focus
    • Select one of the programme’s priority disease areas.
  2. Identify a licensed intervention
    • The intervention must already be licensed and suitable for optimization.
  3. Build an eligible team
    • Include at least a lead applicant and one coapplicant.
    • Ensure regional representation rules are met.
  4. Confirm organisational eligibility
    • Make sure the administering institution is in Africa, South Asia, or South-East Asia.
  5. Design a clinical trial development plan
    • Focus on preparatory work that enables a future clinical trial.
  6. Prepare core technical sections
    • Work plan
    • Stakeholder and community engagement
    • Data management and sharing
    • Capacity building
    • Team structure and roles
  7. Show the pathway to a future RCT
    • Clearly explain how this project will evolve into a later-stage randomized controlled trial.
  8. Build a realistic budget
    • Keep within £200,000 and justify all costs.

Tips for a Strong Proposal

Common Mistakes to Avoid

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Frequently Asked Questions (FAQs)

1. What is the Infectious Disease Clinical Trial Development Grant Programme?

It is a research funding programme that supports clinical trial development projects aimed at improving the use of licensed infectious disease interventions in LMICs.

2. How much funding is available?

Each award can provide up to £200,000 for a project lasting up to 24 months.

3. Which diseases are covered?

Priority areas include:

4. Who can apply?

Eligible applicants must apply as a team of at least 2 members, with:

5. What kind of organisations are eligible?

Eligible administering organisations include:

They must be located in Africa, South Asia, or South-East Asia.

6. Can collaborators receive salary support?

No. Collaborators may contribute expertise or resources, but they cannot receive salary support under the grant.

7. What should the proposal show?

The proposal must show:

Conclusion

The Infectious Disease Clinical Trial Development Grant Programme is a valuable opportunity for LMIC-based research teams to develop strong, scalable clinical trial concepts in priority infectious disease areas.

With up to £200,000 over 24 months, the programme is best suited for teams that can demonstrate regional leadership, trial expertise, strong partnerships, and a clear path toward a future late-stage clinical trial.

For more information, visit Wellcome.

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