Deadline: 10-Aug-22
The National Institutes of Health is seeking applications for the Behavioral and Integrative Treatment Development Program to encourage behavioral intervention development research to test efficacy, conduct clinical trials, examine mechanisms of behavior change, determine dose-response, treatment optimization, and/or ascertain best sequencing of behavioral, combined, sequential, or integrated behavioral and pharmacological:
- drug abuse treatment interventions, including interventions for patients with comorbidities;
- drug abuse treatment and adherence interventions;
- drug abuse treatment and adherence interventions that utilize technologies to boost effects and increase implementability and sustainability;
- interventions to prevent the acquisition or transmission of HIV infection among individuals in drug abuse treatment;
- interventions to promote adherence to drug abuse treatment, HIV and addiction medications; and
- interventions to treat substance misuse and chronic pain.
The objective of this announcement and its companion funding opportunity is to ensure sufficient emphasis and support for Stages I through III of behavioral and integrative treatment research. The supported studies will support translation of scientific knowledge into more efficient behavioral, combined behavioral and pharmacological, integrative, and complementary treatments so that they ultimately can be effectively transported from research to the community.
Areas of Interest
Specific areas of interest include, but are not limited to:
- Research to elucidate purported mechanism of action and targets of behavioral interventions at multiple levels of analysis. This includes determination of underlying biological and/or neurobiological mechanisms (e.g., as measured by imaging methodologies, skin conductance, or other biological/physiological indices) of the interventions associated with the behavioral, cognitive, affective, or social mechanisms of interventions.
- Research that uses innovative technologies (digital therapeutics, including mobile applications and other platforms, virtual reality, wireless monitoring and biofeedback, imaging tools for biofeedback) to develop, improve and systematically measure behavioral interventions including the use of imaging methods to predict outcomes from behavioral interventions. Additionally, neuromodulation devices to augment behavior therapies.
- Research that incorporates of genetic/epigenetic methodologies to help understand the variability in outcomes as result of therapeutic interventions.
- Research that evaluates the use of medications to improve the efficacy of behavioral interventions.
- Research on the essential components of a behavioral treatment, adherence or therapist training intervention.
- Stage II and III treatment development research aimed at facilitating the implementation of an intervention, testing behavioral interventions within primary care settings.
- Research to promote adherence to pharmacotherapies, such as buprenorphine, methadone, depot naltrexone, naloxone, or HAART, in substance abuse treatment populations.
- Studies that develop safe and effective psychosocial interventions to improve the outcomes of pharmacotherapies for SUDs including OUD and overdose reversal.
- Research on tobacco harm reduction strategies such as switching from combustibles to e-cigarettes.
- Research to adapt or modify scientifically supported substance abuse treatments, adherence interventions, or HIV prevention interventions for drug and alcohol users to enhance the application of and boosting treatment potency among health disparities populations.
Duration
The maximum project period is 5 years.
Eligiiblity Criteria
- Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
- The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
- Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Federal Government
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
- Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
- Non-domestic (non-U.S.) Entities (Foreign Institutions)
For more information, visit https://www.grants.gov/web/grants/view-opportunity.html?oppId=340173