Deadline: 26-May-25
The Department of Health and Human Services (DHHS) and Agency for Health Care Research and Quality is inviting proposals for the Large Research Projects for Prevention of Healthcare-Associated Infections to advance the base of knowledge for detection, prevention, and reduction of Healthcare-Associated Infections (HAIs).
AHRQ collaborates with other HHS Agencies to prevent and reduce HAIs and has funded initiatives in all of the settings identified in the HAI NAP: Acute care hospitals; ambulatory settings, such as ambulatory surgical centers, outpatient care clinics and offices, and hemodialysis centers/end-stage renal disease facilities; and long-term care settings.
AHRQ projects have addressed a variety of HAI types, prominently among them: central line-associated bloodstream infection (CLABSI), catheter-associated urinary tract infection (CAUTI), surgical site infection (SSI), ventilator-associated pneumonia (VAP), methicillin-resistant Staphylococcus aureus (MRSA), and Clostridioides difficile.
AHRQ intends to continue supporting research and demonstration projects that address more effective ways to prevent HAIs and promote the wide-scale adoption of evidence-based approaches. This FOA announces the availability of funds to support Large Research Projects, using the R01 mechanism, in the following broad areas of HAI research:
- Determination of the clinical efficacy and effectiveness of preventive interventions, including unintended adverse consequences.
- Characterization and assessment of relevant epidemiological aspects of HAIs, including but not limited to patient risk factors, clinical presentation, and sources of antibiotic-resistant organisms involved in the development of HAIs.
AHRQ is interested in R01 projects directed to any of the healthcare settings – acute care hospitals, ambulatory care settings, and long-term care settings – as scientifically warranted.
AHRQ is interested in all aspects of HAI prevention, including, but not limited to, ambulatory care, ambulatory surgery, long-term care, linkage between the various settings of care to improve tracking and prevention of HAIs, antibiotic stewardship, multidrug-resistant organisms, and prevention of respiratory viral HAIs.
AHRQ is interested in HAI research conducted in under-resourced health care settings.
A companion FOA (PA-21-264) announces the availability of funds to support Large Health Services Research Demonstration and Dissemination Projects, using the R18 mechanism, in the following broad areas of HAI research:
- Demonstration, dissemination, and evaluation of strategies and approaches for prevention and reduction of HAIs.
- Research regarding adoption and implementation (including sustainment and spread/scale-up) of evidence-based approaches for prevention of HAIs.
Funding Information
- Award Budget: The total costs (direct and indirect) for each project awarded under this FOA will not exceed $500,000 in any given year and $2.5 million for the entire project period.
- Award Project Period: The project period may not exceed 5 years.
Eligibility Criteria
- Higher Education Institutions
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- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
- The following types of Higher Education Institutions are always encouraged to apply for AHRQ support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
- Other
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
For more information, visit https://www.grants.gov/web/grants/view-opportunity.html?oppId=334065