Deadline: 7 December 2017
National Institutes of Health is currently inviting applications for its program entitled “Understanding HIV Persistence in Infants” in order to stimulate research in the pathogenesis of perinatal HIV-1 infection by elucidating HIV-1 immune responses in the setting of the infants evolving immune system and mechanisms of establishment and maintenance of HIV-1 latent viral reservoirs.
Areas of Research
- Development of the infant immune system and age-dependent maturation of innate and adaptive immune responses to HIV-1 infection
- Acquisition and development of bNABs to HIV-1 in early life
- Mucosal immune responses to HIV-1 infection
- Role of immune activation, inflammation and their mediators in various tissues or micro biomes on HIV-1 persistence in infants
- Viral and host cellular factors and functions involved in the persistence of HIV-1 infection
- Contribution of latency and low-level ongoing replication to HIV-1 persistence
- Latent reservoir dynamics, including association of duration of viral suppression in relation to time of infection, rate of viral decay, immune status, and other factors
- Contributions of immunity on the size of the latent reservoir, and immunological biomarkers in the prediction of viral rebound
Funding Information
Estimated Total Program Funding: $3,550,000
Eligibility Criteria
- Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
- The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
- Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
- Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
- Non-domestic (non-U.S.) Entities (Foreign Institutions)
- Foreign Institutions
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.
- Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
How to Apply
Interested applicants can download the application material via given website.
Eligible Country: United States
For more information, please visit grants.gov.