Deadline: 9 February 2017
The National Institutes of Health (NIH) is currently seeking proposals from eligible entities for its program titled- Research Centers for Population-based Research to Optimize Cancer Screening (PROSPR) Initiative.
Population-based Research to Optimize the Screening Process (PROSPR) is the National Cancer Institute (NCI) program to promote research aimed at evaluating and improving the cancer screening process. As a part of the reissued PROSPR program, this Funding Opportunity Announcement (FOA) solicits applications for PROSPR UM1 Research Centers. A companion FOA (RFA-CA-16-017) will support a PROSPR U24 Coordinating Center.
The overall goal for PROSPR Research Centers is to enhance understanding of the implementation and effects of screening as practiced in multiple, heterogeneous healthcare environments in the United States.
Program Priorities
Types of observational research studies that may be proposed by a PRC include:
- Comparative effectiveness: compare the benefits and harms of alternative screening regimens (e.g., utilization of different screening modalities, at varying intervals, or tailoring screening strategies to individuals’ underlying risk of developing the cancer of interest; performance of alternative follow-up regimens among those with abnormalities diagnosed at screening).
- Characterizing screening process failures: study determinants of breakdowns at any step of the process including:
- failure to recruit eligible patients into the screening process;
- failure to perform appropriate diagnostic follow-up of those with abnormal screening results; or
- failures of screening or diagnostic tests to detect disease, due to inherent performance characteristics, subjective interpretation by and differential skills of those performing the tests and/or reading the test results, or the environment in which the test is conducted. Study of factors associated with over-screening or over-surveillance (e.g., in ineligibles or overly frequently), or factors associated with false-positive rates for screening or diagnostic tests, are also encouraged.
- Characterization of the health care environment: how do characteristics of the component healthcare systems of the PRC (e.g., organized screening programs, reminder systems, communication between provider teams, incentive structures) positively or negatively impact the cancer screening process?
- Differential experience of racial/ethnic minority or socioeconomically or otherwise disadvantaged populations: how does the screening process differ in medically underserved populations, and what is needed to improve screening-related care in these populations?
- Simulation modeling to determine which potential intervention points within the screening process have the most potential to improve patient outcomes.
Eligibility Criteria
- City or township governments
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Small businesses
- Native American tribal governments (Federally recognized)
- Special district governments
- Others (see text field entitled “Additional Information on Eligibility” for clarification)
- For profit organizations other than small businesses
- Independent school districts
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Public housing authorities/Indian housing authorities
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISISs)
- Eligible Agencies of the Federal Government
- Faith-based or Community-based Organizations
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Non-domestic (non-U.S.) Entities (Foreign Organizations)
- Regional Organizations
- Tribally Controlled Colleges and Universities (TCCUs)
- U.S. Territory or Possession
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
- Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
How to Apply
All eligible entities must apply online via given website.
Eligible Country: United States
For more information, please visit Grants.gov.