Deadline: 9-May-22
The Centers for Disease Control and Prevention (CDC) is pleased to announce a grant opportunity to increase the capacity and capability of newborn screening laboratories to test for newborn screening conditions as recommended by the U.S. Department of Health and Human Services Advisory Committee on Heritable Disorders in Newborns and Children.
This NOFO will also improve newborn screening test performance and test interpretation of dried blood spot newborn screening.
This announcement is only for non-research activities supported by CDC. This Health and Human Services (HHS) Advisory Committee on Heritable Disorders in Newborn sand Children (ACHDNC), and those that might be added to individual state panels by state-level advisory committees or state legislatures. Early detection of these conditions, whose symptoms are not clinically observable at birth, save thousands of infants and children from disability and death through early detection and treatment.
Funding Criteria
- Estimated Total Program Funding: $8,000,000
- Award Ceiling: $500,000
- Award Floor: $250,000
CDC Program Support to Recipients
- Assist in designing, developing, and evaluating laboratory methods, especially with respect to quality assurance/quality control, integration with the CDC Newborn Screening Quality Assurance Program, and consultation with the CDC Molecular Assessment Program.
- Engage in efforts to harmonize newborn screening laboratory results across laboratories using CDC quality control materials.
- Engage in efforts to improve the quality of existing and emerging newborn screening laboratory methods.
- Facilitate communication among recipients and with other state newborn screening programs.
- Promote compatibility of laboratory data from multiple sources by providing common reference materials.
- Provide assistance in development of training materials on laboratory methods, evaluations, risk communication, and other topics for state public health newborn screening programs.
Outcomes
During the period of performance, a successful recipient will execute the strategies and produce outcomes to improve capabilities and capacities of public health newborn screening laboratories. Depending on strategies selected, recipients should work toward the bolded short-term outcomes outlined in the logic model. Depending on the strategies selected by the applicant, the short-term period of performance may include the following:
- Implementation of one or more newborn screening conditions recently added to the U.S. Recommended Uniform Screening Panel(RUSP)
- Number of newborns screened for conditions recommended on the U.S. RUSP
- Increased Positive Predictive Value
- Decreased False Positive rate
- Decreased turnaround Time to screening result call-out
- Applied bioinformatics to move screening towards Next Generation Sequencing
- Improved analytic algorithms for screening interpretation.
Eligibility Criteria
- Unrestricted (i.e., open to any type of entity),
- This NOFO benefits all live born newborns. Applicants should clearly identify the state, territory, and/or tribal lands that they will serve.
For more information, visit Grants.gov.
For more information, visit https://www.grants.gov/web/grants/view-opportunity.html?oppId=335100