Open Call: Local Partnerships for Global Health Security (United States)

The Protecting and Improving Global Health Security by Engaging Local Partners funding opportunity supports projects that strengthen Ghana’s public health system, improve infectious disease prevention, enhance surveillance and laboratory capacity, and build long-term national health security. The program offers an estimated US$125 million in funding to eligible organizations working to strengthen disease detection, emergency preparedness, and public health response.

Protecting and Improving Global Health Security by Engaging Local Partners

Funding Summary

• Funding Organization: U.S. Centers for Disease Control and Prevention (CDC)
• Program: Protecting and Improving Global Health Security by Engaging Local Partners
• Funding Type: Public Health Grant
• Total Estimated Funding: US$125,000,000
• Country Focus: Ghana

About the Program

The Protecting and Improving Global Health Security by Engaging Local Partners program aims to strengthen Ghana’s ability to prevent, detect, and respond to infectious disease threats through sustainable investments in public health systems.

The initiative supports collaboration between national institutions, local organizations, international partners, and other stakeholders to build a resilient health system capable of managing current and emerging public health challenges. It builds on previous investments in disease surveillance, laboratory systems, emergency preparedness, and workforce development while expanding national capacity in advanced disease monitoring and response.

Program Objectives

The program seeks to:

• Strengthen Ghana’s public health system.
• Improve prevention of infectious disease threats.
• Enhance early detection of outbreaks.
• Strengthen disease surveillance systems.
• Improve laboratory capacity.
• Support emergency preparedness and response.
• Develop a skilled public health workforce.
• Strengthen border district surveillance.
• Expand sequencing and bioinformatics capacity.
• Improve long-term national health security.

Priority Areas

Funding supports projects focused on:

• Public health system strengthening.
• Infectious disease prevention.
• Disease surveillance.
• Laboratory system strengthening.
• Emergency response.
• Public health workforce development.
• Border health surveillance.
• Sequencing technologies.
• Bioinformatics.
• Global health security.

Key Program Activities

Supported activities may include:

• Strengthening national disease surveillance systems.
• Improving laboratory infrastructure and diagnostic capacity.
• Expanding surveillance activities in border districts.
• Supporting outbreak preparedness and emergency response.
• Enhancing workforce training for public health professionals.
• Building sequencing and genomic surveillance capacity.
• Developing bioinformatics systems for disease monitoring.
• Strengthening collaboration among public health partners.
• Supporting multisectoral approaches to disease prevention.
• Improving national response coordination during health emergencies.

Expected Outcomes

The initiative aims to achieve:

• Improved prevention of avoidable epidemics.
• Earlier detection of infectious disease threats.
• Faster and more effective outbreak response.
• Stronger laboratory and surveillance systems.
• Increased national preparedness for public health emergencies.
• Enhanced disease monitoring through sequencing and bioinformatics.
• Sustainable public health capacity across Ghana.
• Stronger national leadership in global health security.

Funding Information

• Estimated Total Funding Available: US$125,000,000

The funding will support eligible projects that contribute to strengthening Ghana’s public health infrastructure and global health security objectives.

Who Can Apply?

Eligible applicants include:

• For-profit organizations (other than small businesses).
• Small businesses.
• State governments.
• County governments.
• City or township governments.
• Special district governments.
• Federally recognized Native American Tribal Governments.
• Native American Tribal Organizations (other than federally recognized tribal governments).
• Public and state-controlled institutions of higher education.
• Private institutions of higher education.
• Independent school districts.
• Public housing authorities.
• Indian housing authorities.
• Nonprofit organizations with 501(c)(3) status.
• Nonprofit organizations without 501(c)(3) status.
• Other eligible entities identified in the funding opportunity announcement.

Why This Program Matters

Emerging infectious diseases continue to pose significant threats to national and global health. Strong surveillance systems, well-equipped laboratories, skilled public health professionals, and effective emergency response mechanisms are essential for identifying outbreaks early and limiting their spread.

This funding opportunity strengthens Ghana’s public health infrastructure by supporting sustainable investments that improve disease prevention, detection, preparedness, and response while contributing to broader global health security efforts.

How to Apply

Applicants should follow these steps:

1. Review the complete funding opportunity announcement.
2. Confirm organizational eligibility.
3. Develop a project aligned with the program priorities.
4. Prepare a detailed implementation plan.
5. Develop a comprehensive project budget.
6. Demonstrate organizational and technical capacity.
7. Submit the application according to the official funding requirements.

Tips for Applicants

• Align the project with Ghana’s public health priorities.
• Demonstrate strong technical expertise.
• Include sustainable capacity-building activities.
• Highlight collaboration with local and international partners.
• Develop measurable outcomes and monitoring indicators.
• Clearly explain the project’s long-term public health impact.
• Include realistic implementation timelines and budgets.

Common Mistakes to Avoid

• Proposing activities unrelated to global health security.
• Failing to demonstrate organizational capacity.
• Weak monitoring and evaluation plans.
• Limited collaboration with key stakeholders.
• Incomplete implementation strategies.
• Poor alignment with the funding priorities.
• Insufficient sustainability planning.

Frequently Asked Questions (FAQs)

What is the purpose of this funding opportunity?

The program supports initiatives that strengthen Ghana’s public health system and improve prevention, detection, and response to infectious disease threats.

How much funding is available?

The estimated total funding available is US$125,000,000.

Which country does the program support?

The funding opportunity is specifically focused on strengthening public health capacity in Ghana.

What types of activities are supported?

Eligible activities include disease surveillance, laboratory strengthening, emergency preparedness, workforce development, sequencing, bioinformatics, and border health surveillance.

Who can apply?

Eligible applicants include nonprofit organizations, government agencies, higher education institutions, businesses, tribal organizations, public authorities, and other eligible entities identified in the funding announcement.

What are the expected outcomes?

The program aims to improve epidemic prevention, strengthen disease detection, enhance emergency response, build laboratory capacity, and create sustainable public health systems.

Why is sequencing and bioinformatics included?

Sequencing and bioinformatics improve the ability to monitor pathogens, detect emerging disease variants, support outbreak investigations, and strengthen evidence-based public health decision-making.

Conclusion

The Protecting and Improving Global Health Security by Engaging Local Partners funding opportunity represents a major investment in strengthening Ghana’s public health system and long-term health security. With US$125 million in estimated funding, the program supports collaborative initiatives that enhance disease surveillance, laboratory systems, emergency preparedness, workforce development, and advanced public health capabilities to better prevent, detect, and respond to infectious disease threats.