Deadline: 29-Jun-23
Great Ormond Street Hospital Children’s Charity (GOSH Charity) is inviting project grant applications for Paediatric health research studies focusing on complex or rare diseases.
The call will support research across the spectrum of medical conditions affecting the foetus, neonates and children directly, as well as pregnancy disorders that affect the child. Qualitative and mixed methods research projects, including healthcare management for specific childhood diseases/conditions or groups of closely related conditions, are also welcomed.
All projects must aim to improve understanding of the disease or associated conditions, or to improve outcomes for the affected child. Proposals will be expected to have the potential to lead to new medical developments or improved healthcare (e.g. diagnostic tools or novel interventions) through laboratory and/or clinically based research. Applicants must clearly articulate the route to clinical application and/or potential for patient benefit, regardless of where their proposed studies are positioned along the basic-to-applied research continuum.
Funding Information
- GOSH Charity has made £2 million available for this funding call. It is anticipated that a range of proposals from different investigators and institutions across the UK will be eligible for an award. Therefore, applicants are asked to carefully consider their request for funding and whether it represents good value for money.
- Total costs above £50,000 and up to £250,000 per application will be considered, for a maximum project duration of three years.
- Funding will be provided for the direct costs of research (such as research staff and consumables) but will not cover consultant programmed activities, the salary-time of the Principal Investigator/team leader, nor may it be applied towards PhD studentships.
Research Partners
- They are delighted to extend the reach of this call by offering, in association with the research partners, the possibility of joint funding for projects focusing on their respective areas of interest. They therefore specifically welcome any applications that:
- Aims to lead to treatments or a cure for Ataxia-Telangiectasia
- Aims to lead to treatments for Norrie Disease, with a particular focus on treating the hearing loss
- Aims to advance the understanding and treatment of Dravet Syndrome
- Aims to significantly advance the search to find a cure and/or a treatment for any of the genetic forms of centronuclear and myotubular myopathy. This includes studies on modifiers of disease progression, and studies that would increase an understanding of liver abnormalities in the condition.
- Aims to identify treatments that improve the quality of life for patients with Acrodysostosis.
- Aims to advance research into the DHDDS gene mutations with neurological manifestations, building on understanding of the biochemical underpinning of this disease and screening for potential diseasetargeted therapeutic interventions.
Eligibility Criteria
- This is a national funding call and is open to independent researchers based anywhere in the UK.
- Investigators can apply to this call as a lead applicant if they: hold a salaried, academic research post; are in their first independent position at group-leader level and have sufficient time remaining in their current post to complete the awarded project.
- As a way of increasing and retaining capacity in this critical research area, they are particularly interested in supporting projects from promising early career researchers. To this end, whilst they welcome applications from independent researchers at any level of seniority, if a funding decision is required between applications of equivalent quality, those of early career researchers will be prioritised.
- Awards may not be used to support the salaries of the Principal Investigator/team leader.
For more information, visit GOSH Charity.