Deadline: 21-Dec-22
UK registered organisations can apply for a share of up to £5 million for manufacturing innovation for nucleic acid medicines. This funding is from Innovate UK.
The aim of this competition is to improve the resource efficiency, productivity and scalability for the manufacture of nucleic acid medicines in the UK.
The objective is to stimulate the development and implementation of innovative technologies to improve the resource efficiency, productivity and ability to manufacture nucleic acid-based medicine. This must allow for growth at scale including, but not limited to, emerging products targeting large patient populations.
The nucleic acid-based active ingredients in scope for this competition include but are not limited to:
- Small activating ribonucleic acid (RNA)
- Messenger ribonucleic acid (mRNA), including self-amplifying mRNA
- Antisense RNA or oligonucleotides
- Small interfering, short interfering or silencing RNA
- Short hairpin RNA
- Micro RNA
- DNA.
Specific Themes
- Your project must focus on one or more of the following:
- In-process monitoring, control and release testing
- Maintenance of product critical quality parameters such as purity, potency and viability
- Product characterisation
- Process challenges for increasing the scale of production
- Transfer of technology from small-scale manufacturing to a good manufacturing practice (GMP) manufacturing facility
- Lowering of the cost of goods as final output
- Increase in yield of active ingredient
- Increase in speed of production cycle
- Methods to increase the flexibility of established manufacturing facilities
- Adaptation of processes from batch to continuous production.
Funding Information
- Your project’s total grant funding request must be between £100,000 and £2 million.
Eligibility Criteria
- Your project must:
- Have total costs between £100,000 and £2 million
- Start by 1 June 2023
- End by 31 May 2025
- Last between 12 and 24 months
- Carry out all of its project work in the UK
- intend to exploit the results from or in the UK.
- Lead Organisation
- To lead a project your organisation must:
- Be a UK registered business of any size or a research and technology organisation (RTO), not for profit or public sector organisation
- Collaborate with other UK registered organisations
- Be or involve at least one grant claiming micro, small or medium-sized enterprise (SME).
- To lead a project your organisation must:
- Project Team
- To collaborate with the lead, your organisation must be one of the following UK registered:
- Business of any size
- Academic institution
- Charity
- Not for profit
- Public sector organisation
- Research and technology organisation (RTO)
- To collaborate with the lead, your organisation must be one of the following UK registered:
- Each partner organisation must be invited into the Innovation Funding Service by the lead to collaborate on a project. Once accepted, partners will be asked to login or to create an account and enter their own project costs into the Innovation Funding Service.
Ineligible
- They are not funding projects that are:
- Wholly lipid nanoparticle, bioconjugation or other formulated nucleic acid product or process development
- For medicines discovery
- Manufacturing process innovations using a non-human medicine as the product
- They cannot fund projects that are:
- Dependent on export performance, for example giving a subsidy to a baker on the condition that it exports a certain quantity of bread to another country
- Dependent on domestic inputs usage, for example giving a subsidy to a baker on the condition that it uses 50% UK flour in their product.
For more information, visit https://apply-for-innovation-funding.service.gov.uk/competition/1356/overview/685e8ab1-88ff-481c-8200-618811d7f6a8