Large Health Services Research Demonstration and Dissemination Projects

Deadline: 26-May-25

The Agency for Health Care Research and Quality has announced the applications for Large Health Services Research Demonstration and Dissemination Projects to address strategies and approaches for prevention and reduction of Healthcare-Associated Infections (HAIs).

HAIs are infections that patients acquire during the course of receiving treatment for other conditions within a healthcare setting. These infections are a significant cause of preventable illness and death in the United States. At any given time, about 1 in every 31 hospital patients has an HAI. Tens of thousands of patients lose their lives from HAIs each year, and these infections impose billions of dollars in excess costs annually.

Objectives

AHRQ collaborates with other HHS Agencies to prevent and reduce HAIs and has funded initiatives in all of the settings identified in the HAI NAP: Acute care hospitals; ambulatory settings, such as ambulatory surgical centers, outpatient care clinics and offices, and hemodialysis centers/end-stage renal disease facilities; and long-term care settings. AHRQ projects have addressed a variety of HAI types, prominently among them: central line-associated bloodstream infection (CLABSI), catheter-associated urinary tract infection (CAUTI), surgical site infection (SSI), ventilator-associated pneumonia (VAP), methicillin-resistant Staphylococcus aureus (MRSA), and Clostridioides difficile.
AHRQ intends to continue supporting research and demonstration projects that address more effective ways to prevent HAIs and promote the wide-scale adoption of evidence-based approaches. This FOA announces the availability of funds to support Large Health Services Research Demonstration and Dissemination Projects, using the R18 mechanism, in the following broad areas of HAI research:
- Demonstration, dissemination, and evaluation of strategies and approaches for prevention and reduction of HAIs.
- Research regarding adoption and implementation (including sustainment and spread/scale-up) of evidence-based approaches for prevention of HAIs.

Funding Information

The total costs (direct and indirect) for each project awarded under this FOA will not exceed $500,000 in any given year and $2.5 million for the entire project period.
The project period may not exceed 5 years.

Eligibility Criteria

Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
The following types of Higher Education Institutions are always encouraged to apply for AHRQ support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
Other
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations