Deadline: 1-Feb-22
The Centers for Disease Control and Prevention is accepting applications for Enhancing Capacity for Strategic and Applied Research Activities in Support of Control and Elimination of Malaria and Other Parasitic Diseases.
The purpose of this notice of funding opportunity (NOFO) is to assist with the implementation of research studies that will provide critical information on ways to monitor, control, and potentially eliminate parasitic diseases including malaria. Through this funding announcement, the Division of Parasitic Diseases and Malaria seeks to fund critical research and evaluation activities with the potential to yield high impact public health findings and to improve strategies that will decrease the overall burden of parasitic diseases and increase the health and wellbeing of affected populations. Research topics include identifying and tracking morbidity, developing and testing better diagnostic tools, improving surveillance, and developing and evaluating interventions that can reduce or interrupt transmission of parasitic diseases including reduction of their vectors.
Goals
- Category 1
- Determine the factors associated with schistosomiasis and STH morbidity. For example, what is the prevalence level of these infections which disease is no longer observed in the community? Develop and evaluate improved methods to monitor morbidity (Focus for Year 1).
- Determine WASH levels associated with increased impact of MDA. Validate a WASH assessment tool that can identify community targets to help reduce prevalence (Focus for Year 1).
- Evaluate and validate new methods for diagnosis of schistosomiasis and STH that are cost effective to use in monitoring and evaluating control programs.
- Determine the frequency and geographic level of surveillance that provide reliable data to drive control program decisions as well as rapidly identify hotspots of infection.
- Identify interventions beyond MDA (e.g., snail monitoring and control for schistosomiasis) that can be employed to increase programmatic success.
- As new treatments or new formulations of existing treatments become available for schistosomiasis and soil transmitted helminths, evaluate dose, efficacy, impact, required frequency, and any side effects.
- Improve routine surveillance platforms and ensure that they are collecting high-quality, actionable data, and work with the Ministry of Health to improve utilization of these data
- Category 2
- In coordination with global partners, evaluate community-level case management activities and practices for severe and complicated malaria to strengthen the ability of health facilities and community intervention efforts to provide timely and appropriate care and treatment to vulnerable populations (Focus for Year 1).
- Evaluate surveillance as a core intervention (Focus for Year 1).
- Evaluate novel prevention strategies, such as malaria vaccines, for efficacy and feasibility, and understand how to optimally implement these strategies.
- Evaluate the impact of drug-based strategies – including, but not limited to, intermittent mass test and treat, reactive case detection and treatment, and mass drug administration – on malaria morbidity, mortality, and transmission in a targeted geographic area, transmission focus, or segment of a population.
- Evaluate the continued effectiveness of intermittent preventive treatment during pregnancy and alternative strategies and approaches for prevention of malaria in pregnancy.
- Evaluate the efficacy of novel vector control tools and technologies such as insecticide treated materials, including use of combination insecticide-treated bed nets, insecticidetreated wall liners, spatial repellents, attractive targeted sugar baits.
- Monitor the efficacy of first- and second-line antimalarial drugs.
- Disseminate results from these operational research and prevention activities through written publications, oral presentations, hosting of study tours, or by other means.
- Assist Ministries of Health in translating operational research findings into public health policy and practice in sub-Saharan Africa, and ensure sharing of expertise and research findings with other partners and countries.
Categories
- Schistosomiasis And/Or Soil-Transmitted Helminths In Kenya
- Malaria in Sub-Saharan Africa
Funding Information
- The estimated total funding available, including direct and indirect costs, for the entire 5-year project period is $12 million. The number of awards will be up to 4 awards.
- Budget and Project Period: The estimated total funding (direct and indirect) for the first budget period, 09/30/2022 to 09/29/2023 will be the following:
- Category 1 (Schistosomiasis and/or Soil-Transmitted Helminths in Kenya) – $500,000 per award
- Category 2 (Malaria in Sub-Saharan Africa) – $700,000 per award
- The estimated total funding (direct and indirect) for the entire project period (5 years) will be $12 million. The 5-year project period total funding estimate is:
- Category 1 (Schistosomiasis and/or Soil-Transmitted Helminths in Kenya) – $2.5 million per award
- Category 2 (Malaria in Sub-Saharan Africa) – $3.5 million per award
- Anticipated Number of Awards: 4
- Award Ceiling: $2,400,000 Per Budget Period
- Total Period of Performance Length: 5 year(s)
Target Population
The target population includes persons at risk for schistosomiasis, soil-transmitted helminths, and malaria in affected countries throughout the world. Sub-population target groups within malaria transmission zones should include those most at-risk e.g., children under five years of age and pregnant women.
Eligibility Criteria
- Native American tribal organizations (other than Federally recognized tribal governments)
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Others
- Special district governments
- Independent school districts
- Native American tribal governments (Federally recognized)
- City or township governments
- For profit organizations other than small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Small businesses
- County governments
- Public housing authorities/Indian housing authorities
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Nonprofits (Other than Institutions of Higher Education):
- Nonprofits (Other than Institutions of Higher Education)
- Other:
- Faith-based or Community-based Organizations
- Regional Organizations
- Foreign Organizations are eligible to apply.
For more information, visit Grants.gov.
For more information, visit https://www.grants.gov/web/grants/view-opportunity.html?oppId=335748