Unitaid Call for Proposals: Accelerating Impact of Long-Acting Technologies in Low- And Middle-Income Countries (LMICs)

Deadline: 4 March 2019

Unitaid has announced a Call for Proposals to support development of long-acting products of medicines to treat and/or prevent diseases affecting LMICs, notably HIV, HIV coinfections/comorbidities, TB, and malaria, with broader consideration for management of antimicrobial resistance (AMR). Proposals should include the following elements:

  • repurposing critical standard-of-care medicines into long-acting products, examples of such products may include injectables, implants, oral dosing technologies, or other;
  • enabling sound commercialization to facilitate subsequent uptake and scale in LMICs for resulting products. Considerations include: capacity for adequate and quality-assured production; regulatory strategy for LMICs; licensure and pricing strategies that can facilitate introduction and broad access in LMICs.

Proposals submitted should clearly demonstrate the fit with the objectives set out above, the expected impact and value for money, as well as, the complementarity to similar projects in this area.

Applicants are encouraged to consider products that can be introduced in the market within three to five years (i.e. products that could be eligible for purchase by major funders and countries as relevant and supply capacity created to address demand sufficiently by the end of this timeframe).

Topics which are out of scope for this Call include: a) proposals seeking the development of long-acting products including new chemical entities (NCEs), or new indications for approved drugs, that require full clinical development prior to submission to regulatory approval; b) proposals aiming to implement and/or deliver products at scale.

Proposals that include more than one product, leveraging investments across product-categories, and collaborative partnerships including industry are welcomed. Proposed project governance should consider the integration of a scientific advisory board.

Criteria

The applicant(s) may be:

  • A public or private entity / institution / organization; or
  • A consortium: a group of public and/or private entities / institutions / organizations with one entity / institution or organization acting as the Lead Organization (“LO”),
  • The LO shall assume responsibility, for the project presented in the proposal and shall be the sole signatory of any subsequent legal agreement with UNITAID setting out the terms and conditions of a grant. The LO will be exclusively responsible for undertaking all negotiations and discussions with UNITAID and shall ultimately remain responsible for all results and deliverables under the legal agreement, including those to be accomplished by other consortium members.

How to Apply

Proposals should be submitted electronically at the address given on the website.

For more information, please visit https://unitaid.org/call-for-proposal/accelerating-impact-of-long-acting-technologies-in-low-and-middle-income-countries-lmics/#en

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