Announcement of Call for Proposals on Intervention Effectiveness used in the Elimination of Neglected Tropical Diseases

Deadline: 3 June 2019

The Neglected Tropical Diseases Support Center (NTD-SC) at The Task Force for Global Health is accepting proposals for operational and implementation research to improve the effectiveness of interventions used in the elimination of neglected tropical diseases (NTDs).

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Research proposed for this call will investigate and solve persistent challenges associated with the implementation of NTD programs, focusing on different elements of either mass drug administration (MDA) or morbidity management and disability prevention (MMDP).

With this call, the NTD-SC – which serves as Secretariat of the Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD) –seeks proposals that are nested within national programs and target lymphatic filariasis, onchocerciasis, schistosomiasis and trachoma. Projects will be funded with UK aid from the British government through the NTD-SC which serves as Secretariat for the Coalition for Operational Research on NTDs (COR-NTD). Selected projects should be aligned with WHO’s disease-specific targets and guidelines.

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Although NTD programs have achieved control and elimination targets in many settings, these goals have been hard to attain in some contexts due to implementation challenges. A number of distinct health system, contextual and community factors may be responsible for reducing the overall effectiveness and impact of NTD interventions along the delivery continuum.

Focused operational and implementation research to understand barriers and to test feasible solutions to overcome them can improve the overall effectiveness of these interventions and their equity and impact within NTD programs. The research generated by this call will form the basis of a framework of evidence-based solutions to implementation challenges as well as guide further research to improve intervention effectiveness.

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Proposals should include a clear strategy i) to improve NTD intervention effectiveness so as to support countries toward achieving the control and elimination targets set by the World Health Organization (WHO) and ii) to quantify this improvement. Examples include, but are not limited to:

  • Addressing barriers to accessibility, acceptability, and uptake of an intervention among specific population groups through context-specific approaches.
  • Testing of novel and cost-efficient ways to motivate and sustain the cadre of people who deliver NTD interventions, whether part of the formal health system or part of a non-formal workforce.
  • Developing and testing simplified and effective rapid assessment tools within the community to tailor social mobilization approaches to MDA.
  • Identifying methods to improve community ownership of NTD interventions and document impact.

Geographical Focus

There are no country limitations, but please note that the country of focus should be one with NTD program(s) addressing either MMDP or MDA services.

What will be funded?

  • Research to address barriers to interventions such as mass drug administration or morbidity management and disability prevention
  • Research targeting preventive chemotherapy programs for lymphatic filariasis, onchocerciasis, schistosomiasis and trachoma
  • Research nested within national NTD programs
  • Operational or implementation research

What will NOT be funded?

  • Intervention activities themselves (such as mass drug administration, school-based drug administration, community-based vector control, and social mobilization)
  • Research targeting other diseases – such as innovative and intensified disease management diseases – without a connection to the four diseases of interest
  • Research unrelated to national NTD programs
  • Basic or clinical research

Evaluation Criteria

Applications will be evaluated based on the following:

  • Research intervention must be nested within national NTD programs and respond to documented programmatic needs
  • A plan for measuring the improvement in program performance (including effectiveness, equity) achieved as a result of the research intervention
  • Collaboration between national and international research teams
  • Theory of change guiding the research
  • Scientific merit of the research methods
  • Considerations for scale up of the output
  • Plan for knowledge translation
  • Value for money

How to Apply

Applications must be submitted online via given website.

For more information, please visit

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