Deadline: 28-Sep-2025
The National Institutes of Health (NIH) has announced the funding opportunity BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed) to support the development of innovative theories, models, and methods that advance a quantitative and predictive understanding of brain function across multiple scales, including behavior.
The focus areas of this opportunity are: development of fundamentally new or significantly advanced theories of brain function; mechanistic and/or predictive models of neural circuit activity and behavior grounded in empirical data; novel computational or statistical methods for analyzing neural and behavioral datasets; theories of brain function including embodied computation, multiscale bridging of spatial and temporal dynamics, linking circuit dynamics and function to cell types or connections, and elucidating computational principles of biological neural networks; computational models of neural and behavioral dynamics including mechanistic, interpretable, predictive, and rigorously tested models of neural dynamics and brain-behavior links, models of cognitive processing, and neural-inspired computational architectures; and methods for complex data analysis including innovative computational/statistical methods for dimensionality reduction, data fusion, assimilation of heterogeneous datasets, and signal processing techniques for structure tracking in neural data.
This Notice of Funding Opportunity (NOFO) aims to advance the BRAIN Initiative’s mission to revolutionize understanding of the brain by supporting projects that will create widely available tools for the neuroscience community. Proposed experimental work must be limited to model parameter estimation and testing the validity of the tools delivered.
The initiative anticipates providing $6 million per year to fund up to 15 awards annually, with application budgets expected to range between $150,000 to $350,000 in direct costs per year for project periods of up to three years. Applications are accepted from higher education institutions, non-profit organizations, for-profit organizations including small businesses, local and state governments, tribal governments, and eligible foreign organizations.
For more information, visit Grants.gov.
