Deadline: 10-Nov-2025
The Sustained Viral Resilience Programme sits within the Sculpting Innate Immunity opportunity space and seeks to create a new class of medicines that provide durable, broad-spectrum protection against respiratory viruses by engineering the innate immune system.
The programme’s focus areas are TA1 – Explorers, which aim to provide compelling proof-of-concept evidence that SIIPs are possible through iterative design, building, and testing of SIIP candidates for safety and efficacy across in vitro and in vivo models; TA2 – Accelerators, which develop tools, platforms, models, standards, or datasets to accelerate the process of bringing new SIIP candidates to strong proof-of-concept; and TA3 – Translators, which conduct research that facilitates the clinical translation and future commercialisation of SIIPs, smoothing the pathway from technical proof-of-concept to real-world impact.
The programme has allocated a total funding of £46 million to support these thematic areas. The Explorers stream has an expected budget of £34 million, supporting around five teams with grants between £5 million and £8 million each. The Accelerators stream has an expected budget of £10 million, expected to fund two teams with grants of £5 million each. The Translators stream has an expected budget of £2 million, supporting two teams with grants of £1 million each.
Eligibility for participation extends across the research and development ecosystem, including individuals, universities, research institutions, small, medium, and large companies, charities, and public sector research organisations. Applicants are encouraged to collaborate, and many may apply as a consortium of two or more organisations under a single lead applicant who will receive and distribute funding if successful.
Through this initiative, the programme seeks to accelerate the creation of groundbreaking SIIP technologies that will enhance preparedness and resilience against future viral threats by leveraging innovative research and collaboration across scientific disciplines.
For more information, visit ARIA.
