DHHS/NIH Call for Proposals: Implementation Research to Develop Interventions for People Living with HIV

Deadline: 7 August 2017

The National Institutes of Health (NIH), U.S. Department of Health and Human Services, is currently seeking applications for its program titled “Implementation Research to Develop Interventions for People Living with HIV (PRECluDE)”.

The program aims to implement research in the delivery of proven effective interventions for co-occurring heart, lung, blood, and sleep (HLBS) diseases and conditions among people living with HIV/AIDS.

The intent of this program is to stimulate the use of late-stage T4 translation research and implementation science strategies to address barriers that impede the scale-up and application of proven effective interventions in community and clinical settings for the prevention, control, and treatment of co-morbid HLBS conditions for people living with HIV.

Research Areas

Potential research examples include but are not limited to those listed below:

  • Pharmacologic interventions: Identification of deficiencies in the delivery of proven-effective pharmacologic treatment interventions for comorbid HLBS disorders in PLWHIV.
  • Implementation Barriers to Successful Adoption: Research that utilizes a T4 implementation research framework to address the barriers that impede scale-up of preventive care of CVD by addressing multilevel barriers at the community, provider, and patient levels to facilitate better preventive care for PLWHIV. Research that explores the adoption of significant evidence-based practice and guidelines for patients infected with HIV to receive preventive care of CVD.
  • Hematological and vascular complications due to HIV: Uptake of interventions with fidelity for hematologic dysfunctions including anemia, chronic thrombocytopenia, endothelial dysfunction, and thrombophilia using guidelines currently available for treating PLWHIV.
  • Sleep Disturbances: Management of sleep disturbances for PLWHIV, including insomnia and obstructive sleep apnea using evidenced-based approaches and T4 translational research.
  • Implementation strategies for at-risk populations: T4 translation research to improve implementation strategies associated with HIV at-risk populations including prison release populations, marginalized individuals, and LGBT and transgender populations, homeless populations and other defined at-risk populations are strongly encouraged. Racial/ethnic minority, rural and other underserved populations are of particular interest for the development of effective T4 translation research models.
  • Adopting and Adapting Chronic Care Models (CCM) for COPD: Adaptation of evidenced-based CCM for COPD and/or other lung diseases among PLWHIV to improve outcomes, including marginalized groups with significant risk factors and health disparities. Late-stage T4 translational research using CCM that address HIV-positive veterans suffering from COPD and emphysema is an area of high interest
  • Multi-level implementation strategies: Tools that incorporate education and decision support into routine care, promote a team approach, and encourage an active but efficient interaction with PLWHIV using innovative technologies.

Award Information

Application budgets should reflect the actual needs of the proposed project and are limited to a maximum of $500,000 direct costs per year.

Eligibility Criteria

  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Private institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • City or township governments
  • For profit organizations other than small businesses
  • Native American tribal governments (Federally recognized)
  • Special district governments
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • State governments
  • Others
  • Independent school districts
  • Public and State controlled institutions of higher education
  • County governments
  • Other Eligible Applicants include the following:
    • Alaska Native and Native Hawaiian Serving Institutions;
    • Asian American Native American Pacific Islander Serving Institutions (AANAPISISs);
    • Eligible Agencies of the Federal Government;
    • Faith-based or Community-based Organizations;
    • Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs);
    • Indian/Native American Tribal Governments (Other than Federally Recognized);
    • Non-domestic (non-U.S.) Entities (Foreign Organizations);
    • Regional Organizations;
    • Tribally Controlled Colleges and Universities (TCCUs) ;
    • U.S. Territory or Possession;
    • Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
    • Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

How to Apply

Interested entities must apply online via given website.

Eligible Country: U.S.

For more information, please visit Grants.gov.

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